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Table 1 Summary of clinical parameters of Creutzfeldt-Jakob patients enrolled with post mortem brain tissue samples in this study

From: Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia

Age Sex Diagnosis Subtype Disease duration [months] 14–3-3 RT-Quic
F 69 CJD VV1 9 + +
M 72 CJD MM/MV1 n.a. n.a. n.a.
F 78 CJD MM/MV1 n.a. n.a. n.a.
F 59 CJD MV2K 45 n.a. n.a.
M 78 CJD MV2K + C 10 n.a.