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Table 1 Demographics of human cases used to generate experimental lysate

From: Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils

 

Age at onset

Age at death

Pathology diagnosis

Braak stage

Thal phase

CERAD score

Control 1

N/A

82

Cerebrovascular arteriolosclerosis

I/II

2

C1

Control 2

N/A

52

No neuropathology diagnosis

I/II

2

C1

MSA 1

58

67

MSA-C/OPCA

–

0

C0

MSA 2

68

71

MSA-P/SND

–

2

C1

  1. MSA-C multiple system atrophy-cerebellar, OPCA olivo-ponto-cerebellar atrophy, MSA-P multiple system atrophy-parkinsonism, SND striatonigral degeneration
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Acta Neuropathologica Communications

ISSN: 2051-5960

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