Fig. 2
From: APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice
Effects of APOE genotype and sex on amyloid plaque dynamics. a Representative pseudo-colored images show relative circularity of ThioS-positive plaques, with intensity of labeling indicated by brightness (purple/black = low and yellow/white = high), across sex and APOE genotype. Scale bars = 5 μm. b Quantification of plaque circularity in male (M) and female (F) EFAD mice with APOE3 (open bars) and APOE4 (filled bars) genotypes. Numbers of mice analyzed per group are as follows: male E3FAD (n = 6), female E3FAD (n = 5), male E4FAD (n = 5), and female E4FAD (n = 6). * denotes p < 0.05