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Table 2 Patient-derived pediatric glioma tumor and normal brain tissue specimens analyzed

From: Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease

  Tumor Tissue (n = 50) Normal Tissue (n = 3)
Gender Male 27 (54) 2 (66.67)
Female 23 (46) 1 (33.33)
Age < 5 years 7 (14) 2 (66.67)
5–10 years 19 (38) 1 (33.33)
> 10 years 24 (48) 0
Anatomic Location Brainstem 18 (36) 3 (100)
Thalamus 10 (20) 0
Cerebellar Hemisphere 9 (18) 0
Cerebral Hemisphere 13 (26) 0
WHO Grade I 12 (24) N/A
II 7 (14) N/A
III 10 (20) N/A
IV 21 (42) N/A
  1. Formalin fixed paraffin embedded pediatric glioma tumor tissue (n = 50) and normal brainstem tissue specimens (n = 3) were submitted for immunohistochemical (IHC) analysis. Gender, age, tumor anatomical location and WHO-grade of analyzed specimens are summarized. Number in parentheses indicate percentage of total cohort