Table 1 Genetic alterations identified by NGS
From: Coexisting FGFR3 p.K650T mutation in two FGFR3-TACC3 fusion glioma cases
| Â | Surgery 1 Infiltrating glioma, WHO grade II | Surgery 2 Glioblastoma, WHO grade IV |
Patient 1 | FGFR3 p.K650 T (MAF = 4%) FGFR3-TACC3 fusion | FGFR3 p.K650 T (MAF = 29%) NF1 p.F443C TERT c.-124C > T FGFR3-TACC3 (COSF1353) |
| Â | N/A | Surgery 1 Glioblastoma, WHO grade IV |
Patient 2 | N/A | FGFR3 p.K650 T (MAF = 12%) TERT c.-146C > T FGFR3-TACC3 (COSF1348) |