| Univariate analysis | Multivariate analysis | |
---|---|---|---|
 | P value | P value | HR |
[PFS] | |||
 High age | 0.0004* | 0.005* | 1.03 (1.01–1.05)# |
 High KPS score | 0.10 | 0.28 | 0.99 (0.97–1.01)# |
 Gross total resection | 0.02* | 0.17 | 0.75 (0.49–1.13) |
 PIK3CA mutation | 0.03* | 0.01* | 2.89 (1.30–5.90) |
 IDH1 mutation | < 0.0001* | 0.002* | 0.10 (0.006–0.50) |
 MGMT promoter methylation | < 0.0001* | < 0.0001* | 0.33 (0.21–0.52) |
[OS] | |||
 High age | 0.0004* | 0.003* | 1.03 (1.01–1.05)# |
 High KPS score | 0.047* | 0.32 | 0.99 (0.96–1.01)# |
 Gross total resection | 0.11 | 0.53 | 0.87 (0.55–1.35) |
 PIK3CA mutation | 0.19 | 0.049* | 2.32 (1.00–4.88) |
 IDH1 mutation | < 0.0001* | 0.02* | 0.15 (0.008–0.74) |
 MGMT promoter methylation | < 0.0001* | < 0.0001* | 0.27 (0.17–0.44) |