Iba-1 positive cells (cells/mm3) | ||||||
---|---|---|---|---|---|---|
Brain region | Genotype | Post-injection time | Right hemisphere | Left hemisphere | ||
Treatment | Treatment | |||||
Saline-injection | α-synuclein-injection | Saline-injection | α-synuclein-injection | |||
GL | WT | 2 m | 8600 ± 475 | 9726 ± 1253 | 10,463 ± 931 | 8519 ± 1543 |
4 m | 1359 ± 199.1 | 3028 ± 618.1 | 856 ± 348.1 | 2617 ± 613.9 | ||
TG | 2 m | 7583 ± 778.3 | 9249 ± 2388 | 7860 ± 548 | 10,569 ± 1451 | |
EPL | WT | 2 m | 8260 ± 1297 | 9412 ± 538.3 | 8828 ± 594.3 | 7514 ± 1019 |
4 m | 833.4 ± 124.5 | 1086 ± 234.2 | 639.5 ± 303.8 | 1613 ± 582.3 | ||
TG | 2 m | 7421 ± 782 | 8102 ± 482 | 7543 ± 531 | 6762 ± 544 | |
MiL | WT | 2 m | 8939 ± 2174 | 10,807 ± 1040 | 8921 ± 1831 | 9984 ± 1285 |
4 m | 935.6 ± 449.1 | 1162 ± 289.6 | 314.3 ± 98.62 | 1599 ± 642.4 | ||
TG | 2 m | 9080 ± 521 | 4513 ± 1421 | 10,296 ± 549 | 6338 ± 1048 | |
IPL | WT | 2 m | 12,870 ± 3512 | 11,089 ± 1404 | 13,703 ± 279.3 | 10,294 ± 1572 |
4 m | 1134 ± 402.8 | 1066 ± 306.5 | 948.7 ± 481.7 | 2209 ± 1070 | ||
TG | 2 m | 14,126 ± 1671 | 8969 ± 4074 | 12,480 ± 2987 | 9101 ± 3479 | |
GrL | WT | 2 m | 9897 ± 361.6 | 10,597 ± 733.6 | 10,044 ± 321.80 | 8839 ± 1185 |
4 m | 827.8 ± 230.5 | 1301 ± 364.3 | 265.6 ± 62.71 | 1659 ± 662.9 | ||
TG | 2 m | 8646 ± 876 | 11,231 ± 1751 | 9316 ± 934 | 10,632 ± 567 | |
AON | WT | 2 m | 10,536 ± 1506 | 10,687 ± 2337 | 10,031 ± 1196 | 8168 ± 1690 |
4 m | 700.3 ± 425.8 | 555.7 ± 385.8 | 0 ± 0 | 321.1 ± 230.7 | ||
TG | 2 m | 8665 ± 1015 | 8084 ± 2493 | 8810 ± 703 | 9251 ± 1681 | |
Pir | WT | 2 m | 8202 ± 1371 | 8798 ± 1763 | 8395 ± 471.5 | 8241 ± 2339 |
4 m | 108 ± 74.58 | 330.7 ± 143.7 | 0 ± 0 | 684.8 ± 569.9 | ||
TG | 2 m | 7151 ± 882 | 9312 ± 1061 | 9025 ± 546 | 6999 ± 507 |