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Table 2 Unbiased stereological quantification of Iba-1. Mean ± SEM represent Iba-1-positive cells/mm3 in the OB layers, AON and Pir. Statistical analysis was focused on comparisons: genotype in the right hemisphere, left hemisphere, interhemispheric differences in WT and TG. For statistical data, see Additional file 4: Tables S10-S13. For abbreviations, see list

From: Neurodegeneration and contralateral α-synuclein induction after intracerebral α-synuclein injections in the anterior olfactory nucleus of a Parkinson’s disease A53T mouse model

Iba-1 positive cells (cells/mm3)
Brain region Genotype Post-injection time Right hemisphere Left hemisphere
Treatment Treatment
Saline-injection α-synuclein-injection Saline-injection α-synuclein-injection
GL WT 2 m 8600 ± 475 9726 ± 1253 10,463 ± 931 8519 ± 1543
4 m 1359 ± 199.1 3028 ± 618.1 856 ± 348.1 2617 ± 613.9
TG 2 m 7583 ± 778.3 9249 ± 2388 7860 ± 548 10,569 ± 1451
EPL WT 2 m 8260 ± 1297 9412 ± 538.3 8828 ± 594.3 7514 ± 1019
4 m 833.4 ± 124.5 1086 ± 234.2 639.5 ± 303.8 1613 ± 582.3
TG 2 m 7421 ± 782 8102 ± 482 7543 ± 531 6762 ± 544
MiL WT 2 m 8939 ± 2174 10,807 ± 1040 8921 ± 1831 9984 ± 1285
4 m 935.6 ± 449.1 1162 ± 289.6 314.3 ± 98.62 1599 ± 642.4
TG 2 m 9080 ± 521 4513 ± 1421 10,296 ± 549 6338 ± 1048
IPL WT 2 m 12,870 ± 3512 11,089 ± 1404 13,703 ± 279.3 10,294 ± 1572
4 m 1134 ± 402.8 1066 ± 306.5 948.7 ± 481.7 2209 ± 1070
TG 2 m 14,126 ± 1671 8969 ± 4074 12,480 ± 2987 9101 ± 3479
GrL WT 2 m 9897 ± 361.6 10,597 ± 733.6 10,044 ± 321.80 8839 ± 1185
4 m 827.8 ± 230.5 1301 ± 364.3 265.6 ± 62.71 1659 ± 662.9
TG 2 m 8646 ± 876 11,231 ± 1751 9316 ± 934 10,632 ± 567
AON WT 2 m 10,536 ± 1506 10,687 ± 2337 10,031 ± 1196 8168 ± 1690
4 m 700.3 ± 425.8 555.7 ± 385.8 0 ± 0 321.1 ± 230.7
TG 2 m 8665 ± 1015 8084 ± 2493 8810 ± 703 9251 ± 1681
Pir WT 2 m 8202 ± 1371 8798 ± 1763 8395 ± 471.5 8241 ± 2339
4 m 108 ± 74.58 330.7 ± 143.7 0 ± 0 684.8 ± 569.9
TG 2 m 7151 ± 882 9312 ± 1061 9025 ± 546 6999 ± 507
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