Table 2 AD pathology in the different CJD subtypes and strains
Histotypes, n (%) | Strains, n (%) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
MM(V)1 | VV2 | MV2K | Other | p | M1 | V2 | Other | p | |
ABC score | |||||||||
Not | 117 (35.6) | 29 (47.5) | 15 (39.5) | 12 (54.5) | 0.326 | 117 (35.6) | 44 (44.4) | 12 (54.5) | 0.178 |
Low | 182 (55.3) | 29 (47.5) | 21 (55.3) | 8 (36.4) | 182 (55.3) | 50 (50.5) | 8 (36.4) | ||
Intermediate/High | 30 (9.1) | 3 (4.9) | 2 (5.3) | 2 (9.1) | 30 (9.1) | 5 (5.1) | 2 (9.1) | ||
Thal phase | |||||||||
0 | 117 (35.6) | 29 (47.5) | 15 (39.5) | 12 (54.5) | 0.251 | 117 (35.6) | 44 (44.4) | 12 (54.5) | 0.087 |
1–2 | 99 (30.1) | 15 (24.6) | 13 (34.2) | 6 (27.3) | 99 (30.1) | 28 (28.3) | 6 (27.3) | ||
3 | 69 (21.0) | 12 (19.7) | 8 (21.1) | – | 69 (20.1) | 20 (20.2) | – | ||
4–5 | 44 (13.4) | 5 (8.2) | 2 (5.3) | 4 (18.2) | 44 (13.4) | 7 (7.1) | 4 (18.2) | ||
CAA | |||||||||
not CAA | 229 (69.6) | 47 (77.0) | 29 (76.3) | 17 (77.3) | 0.519 | 229 (69.6) | 76 (76.8) | 17 (77.3) | 0.330 |
CAA | 100 (30.4) | 14 (23.0) | 9 (23.7) | 5 (22.7) | 100 (30.4) | 23 (23.2) | 5 (22.7) | ||
Braak stage | |||||||||
0 − + | 163 (49.5) | 38 (62.3) | 28 (73.7) | 13 (59.1) | 0.089 | 163 (49.5) | 66 (66.7) | 13 (59.1) | 0.045 |
I-II | 126 (38.3) | 18 (29.5) | 8 (21.1) | 6 (27.3) | 126 (38.3) | 26 (26.3) | 6 (27.3) | ||
> III | 40 (12.2) | 5 (8.2) | 2 (5.3) | 3 (13.6) | 40 (12.2) | 7 (7.1) | 3 (13.6) | ||
n | 329 | 61 | 38 | 22 | 329 | 99 | 22 | ||