Acta Neuropathologica Communications

Table 5 Genes most strongly associated to cortisol levels and disease duration

From: Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis

		Cortisol				Duration of MS
		Gene	Corr	P		Gene	Corr	P
Positive correlations	1	RXRA	0.88	9.1E-09	1	NFE2	0.74	6.8E-04
	2	HEYL	0.83	2.1E-07	2	CHODL	0.72	1.1E-03
	3	PDGFA	0.83	2.9E-07	3	SLC16A6	0.70	1.9E-03
	4	RND3	0.83	3.5E-07	4	DEFB1	0.68	2.5E-03
	5	GJA4	0.82	3.9E-07	5	PSPH	0.68	2.8E-03
	6	IGFBP4	0.82	5.1E-07	6	MYB	0.67	3.2E-03
	7	IL7R	0.81	8.7E-07	7	GDF10	0.67	3.2E-03
	8	NPTX2	0.80	1.3E-06	8	CST7	0.67	3.3E-03
	9	MAOA	0.80	1.8E-06	9	CNTN3	0.67	3.5E-03
	10	TLN2	0.80	1.8E-06	10	HOXA6	0.67	3.6E-03
Negative correlations	1	ANKRD16	−0.82	5.5E-05	1	MSRA	−0.80	1.2E-04
	2	ALKBH3	−0.78	2.1E-04	2	NBR2	−0.71	1.6E-03
	3	DNM2	−0.78	2.5E-04	3	GNG7	−0.67	3.1E-03
	4	TMEM185B	−0.77	2.7E-04	4	SFPQ	−0.67	3.4E-03
	5	FIBP	−0.77	2.8E-04	5	APC	−0.67	3.6E-03
	6	SERAC1	−0.77	3.0E-04	6	SNX8	−0.63	7.0E-03
	7	PLS3	−0.76	3.8E-04	7	COL20A1	−0.61	9.3E-03
	8	ATP5C1	−0.76	4.0E-04	8	CTTNBP2NL	−0.60	1.1E-02
	9	PDE6B	−0.76	4.2E-04	9	RAI14	−0.59	1.2E-02
	10	OPALIN	−0.75	4.9E-04	10	ADAM10	−0.58	1.4E-02

Corr correlation coefficient, P p-value

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ISSN: 2051-5960

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