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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis

Fig. 5

Validation of expression profiles of selected genes by qPCR. Genes were selected for validation on the basis of clear association with HPA-axis activity and/or disease severity in MS patients, as described in detail in the text (Results section). Note that expression of HEYL, IL7R, IGFB, GJA4, and TGM2 is significantly increased in MS patients with high cortisol CSF levels, compared to both control subjects and MS patients with low cortisol. Con = control subjects; AU = arbitrary units; *p < 0.05; **p < 0.001

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Acta Neuropathologica Communications

ISSN: 2051-5960

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