Fig. 4

Cluster analysis of absolute expression of genes involved in inflammation and gluco-corticoid signaling. a Cluster analysis based on genes included in the GO classes ‘regulation of acute inflammatory response’, ‘chronic inflammatory response’, ‘macrophage differentiation’, and ‘microglial cell activation’. b Cluster analysis based on genes included in the GO classes ‘glucocorticoid-receptor signaling pathway’, ‘cellular response to glucocorticoids’, and ‘glucocorticoid biosynthetic process’. Underlined are genes for which expression differed significantly between MS patients with mild and severe disease. Genes written in bold and italic show a significant difference between patients with high and low cortisol