Fig. 4

RD3+ and RD4+ (a) or anti-4R+ (b) neurons of the BNM in cases of MCA territory infarcts and putaminal hemorrhages. There were more anti-RD3 antibody immunoreactive (RD3+) neurons when there were more anti-RD4 antibody immunoreactive (RD4+) neurons, regardless of Braak stage. Except for stage V or VI (r = 0.26, p = 0.83), the numbers of RD3+ and RD4+ neurons were strongly correlated (total: r = 0.78, p < 0.01; stage I or II: r = 0.83, p < 0.01; stage III or IV: r = 0.82, p = 0.046) (a). The total number of RD3+ and 4R+ neurons or in stage I or II were strongly correlated (total: r = 0.78, p < 0.01; stage I or II: r = 0.69, p < 0.01), whereas there was no correlation in stage III or IV (r = − 0.14, p = 0.78) or stage V or VI (r = − 1.00) (b)