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Table 2 Geometric mean relative expression of HERV-K RNA in ALS cases and controls

From: Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis

 

HERV-K gag

HERV-K pol

HERV-K env

HERV-K gag

HERV-K pol

HERV-K env

Normalisation methoda

GAPDH

GAPDH

GAPDH

XPNPEP1

XPNPEP1

XPNPEP1

ALS

1.001

1.025

0.975

0.868

0.888

0.845

Control

1

1

1

1

1

1

p value

0.677

0.671

0.990

0.113

0.095

0.055

Statistical significance

NSb

NS

NS

NS

NS

NS

  1. a Normalisation against either GAPDH or XPNPEP1 reference genes
  2. b NS = the difference was not statistically significant at p < 0.05