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Table 1 Histological features of NMDAR-E associated ovarian teratomas

From: Immunopathological characterization of ovarian teratomas associated with anti-N-methyl-D-aspartate receptor encephalitis

Case #

Teratoma Grading

CNT Cystic/Solid

PNT /ENT

Inflammatory infiltrates in contact with CNT

TLS in contact with CNT

1

Immature (Grade 1)

Yes/Yes

No/Yes

++

0

2

Immature (Grade 2)

Yes/Yes

Yes/No

+++

0

3

Immature (Grade 2)

No/Yes

Yes/Yes

+

0

4*

Mature

Yes/Yes

No/No

+

0

5*

Mature

No/Yes

Yes/No

+

1

6*

Mature

Yes/Yes

No/No

+

1

7

Mature

Yes/No

No/No

+

0

8

Mature

Yes/Yes

No/No

++

0

9

Mature

Yes/No

No/No

++

0

10

Mature

No/Yes

No/No

++

1

11

Mature

Yes/Yes

Yes/Yes

++

0

12

Mature

No/No

No/No

NA

NA

13

Mature

Yes/Yes

No/No

++

0

14

Mature

Yes/Yes

No/No

+++

1

15

Mature

Yes/No

Yes/No

++

0

16

Mature

Yes/No

Yes/Yes

++

0

17

Mature

No/Yes

No/No

+

0

18

Mature

Yes/Yes

No/Yes

++

1

19

Mature

Yes/Yes

Yes/No

+++

1

20

Mature

Yes/Yes

Yes/No

+

1

21

Mature

No/Yes

Yes/No

+++

1

22

Mature

No/Yes

No/No

++

1

23

Mature

No/Yes

No/No

++

1

24

Mature

Yes/No

No/No

++

1

25

Mature

Yes/No

No/No

+++

0

26

Mature

No/Yes

No/Yes

+

1

27

Mature

No/Yes

No/Yes

+++

1

  1. NMDAR-E: Encephalitis with anti-NMDAR antibodies; CNT: central nervous system-like teratomatous tissue; PNT: peripheral nervous tissue; ENT: Enteric nervous tissue. * Cases presenting histological features resembling glioma; TLS: Tertiary Lymphoid Structures; NA: not applicable