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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis

Fig. 2

Orthogonal validation of molecular classification of ABs. Orthogonal testing including DNA methylation profiling, BRAFV600E sequencing, and MN1 and RELA FISH was performed on ABs with sufficient material. Supervised analysis was performed using the random forest methylation class prediction algorithm version 11b2 (www.molecularneuropathology.org). Recurrent tumors are indicated by “r”

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Acta Neuropathologica Communications

ISSN: 2051-5960

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