Fig. 6From: LRRK2 inhibition does not impart protection from α-synuclein pathology and neuron death in non-transgenic miceα-synuclein pathology in other regions is not altered with MLi-2 treatment. α-Synuclein pathology from 4 other regions was assayed via quantification of pS129 staining in two representative sections for each mouse. Representative staining is shown for the ventral tegmental area (a), the hippocampus (c), the posteromedial cortical amygdaloid nucleus (e) and the visual cortex (g). The quantification of the percentage area occupied with pathology is quantified for each region (b, d, f, h). All plots are means and error bars represent s.e.m. with individual values plotted. VTA p = 0.5671, Hipp p = 0.7387, PMCo p = 0.4142, V p = 0.9387, unpaired t testsBack to article page