Fig. 7

α5-PKO mice show decreased inflammatory cell infiltration after ischemic stroke. a Representative images of Ly6G (red) staining in the penumbra of control and α5-PKO brains at days 1, 2 and 7 after injury. Scale bar = 50 μm. b Quantification showing reduced extravasation of Ly6G⁺ neutrophils in the penumbra of α5-PKO brains at days 1 and 2 but not 7 after injury. n = 5. c Representative images of CD3 (red) staining in the penumbra of control and α5-PKO brains at days 1, 2 and 7 after injury. Scale bar = 50 μm. d Quantification showing reduced extravasation of CD3⁺ lymphocytes in the penumbra of α5-PKO brains at days 1, 2 and 7 after injury. n = 5. e Representative images of CD68 (red) staining in the penumbra of control and α5-PKO brains at days 1, 2 and 7 after injury. Scale bar = 50 μm. f Quantification showing reduced extravasation of CD68⁺ mononuclear cells in the penumbra of α5-PKO brains at days 1 and 2 but not 7 after injury. n = 5. * p < 0.05, compared to controls at the same time points