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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Mural cell-derived laminin-α5 plays a detrimental role in ischemic stroke

Fig. 3

Tight junctions are unaffected in α5-PKO mice under homeostatic conditions. a,b Representative images of ZO-1 (green)/CD31 (red) (a) and Claudin-5 (green)/CD31 (red) (b) staining in the cortex of control and α5-PKO mice. Scale bar = 50 μm. c Representative western blotting and quantification of ZO-1 and Claudin-5 levels in the cortex of control and α5-PKO mice. n = 4. d TEM images showing normal tight junction structure in control and α5-PKO brains. Black arrowheads indicate tight junctions. TEM, transmission electron microscopy. Scale bar = 800 nm

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