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Table 8 Distribution of cases with different levels of local Aβ pathology in the mossy fiber and Schaffer collateral pathway regions

From: Pathogenic tau modifications occur in axons before the somatodendritic compartment in mossy fiber and Schaffer collateral pathways

Local Aβ Plaques

% Cases (N)

(CA1 Str. Rad.)

% Cases (N)

(CA3 Layer)

% Cases (N)

(CA3 Str. Luc.)

% Cases (N)

(DG Layer)

0

55.8 (24)

78.9 (30)

84.2 (32)

59.0 (23)

1

2.3 (1)

7.9 (3)

7.9 (3)

7.7 (3)

2

11.6 (5)

5.3 (2)

0 (0)

12.8 (5)

3

7.0 (3)

2.6 (1)

5.3 (2)

10.3 (4)

4

4.7 (2)

2.6 (1)

0 (0)

2.6 (1)

≥5*

18.6 (8)

2.6 (1)

2.6 (1)

7.7 (3)

  1. Aβ amyloid-β, Str.Rad Stratum radiatum, CA cornu ammonis, Str. Luc stratum lucidum, DG dentate granule, *full range was from 5 to 13 plaques