Skip to main content
Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Pathogenic tau modifications occur in axons before the somatodendritic compartment in mossy fiber and Schaffer collateral pathways

Fig. 5

AT8+ and TNT2+ tau pathologies are highly colocalized. Hippocampal sections were stained with AT8 and TNT2 tau antibodies. (a) Both AT8 and TNT2 are highly colocalized within hippocampal pyramidal neuronal inclusions (CA1 region depicted) as previously demonstrated [41]. (b) Neurites within the CA3 Str. Luc., the axonal region for mossy fibers, showed a high level of colocalization with AT8 and TNT2 tau antibodies. (c) Similarly, neurites in the CA1 Str. Rad., the axonal region for Schaffer collaterals, demonstrated extensive colocalization between AT8 and TNT2. Scale bars are 25 μm

Back to article page