Fig. 2
From: White matter capillaries in vascular and neurodegenerative dementias
Microvascular pathology in the frontal WM in dementia a-h, Low and High power representative images of COL4 (a, b, c, e, g), GLUT-1 (d, f) and CD34 + COL4 (h) immunostained capillaries and microvessel in the WM. Collapsed and string vessels (arrows) were observed using both markers in VaD and PSD with similar profiles in all dementias. e, a microaneurysm-like structure (arrow) in a PSD case detected using COL4. f, a GLUT-1 immunmopostivie tortuous capillary (arrows) in AD. g, COL4 immunopositive ‘bagged’ vessel with increased perivascular space in a PSD case. h, CD34 and COL4 positive profiles of arterioles and capillaries at the juxtaposition of the grey and WM showing several collapsed and string capillaries (arrows). Scale bar represents 25 μm (a, b, c and d); 50 μm (e, f, and g); 100 μm (h)