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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma

Fig. 4

Protein expression of SGmic and SGmac markers in freshly isolated microglia and spleen monocytes/macrophages. (a) Protein expression of SGmic and SGmac genes and reference markers (Cx3cr1, Cd11b, CD45, Ccr2) in microglia and spleen monocytes/macrophages. IBAQ intensities of each protein normalized to Gapdh intensity are shown. (b) Proteomic data were analyzed by a column-wise analysis using a two-sample t-test and a Benjamini-Hodgberg-based FDR < 0.05. T-test difference of SGmic, SGmac and reference marker expression in microglia relative to spleen monocytes/macrophages is shown (n = 4)

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