Fig. 6From: The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer’s diseaseRepresentation of gene ontology enrichment in mice with constitutive depletion of APMAP, according to biological process (a), molecular function (b) and cellular compartment (c). Label-free quantitative proteomics (procedure described in details in the Materials and Methods section) was used to identify proteins differentially expressed in the brains of APMAP-KO mice. Significantly enriched GO terms (p-value < 0.05) were identified by comparing the list of 113 significantly altered proteins (Additional file 2: Table S1) against the whole list of 2747 detected proteins (Additional file 2: Table S1) using the 1D enrichment tool in PerseusBack to article page