Fig. 11
From: Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth
Benztropine prevents tumor growth and displays a synergistic antitumoral effect when associated with oxaliplatin in an ectopic model of colorectal cancer. Tumor size in mice injected subcutaneously into the back with 106 CT26 cells and treated with vehicle, oxaliplatin, oxaliplatin associated with benztropine or benztropine alone. Data are mean ± SEM of 8 tumor volume under each condition. *p < 0.05, **p < 0.01, ***p < 0.001 versus vehicle