Fig. 2
From: ‘Dusty core disease’ (DuCD): expanding morphological spectrum of RYR1 recessive myopathies
Immunoistochemestry and Immunofluorescence of DuCD and CCD. IHC showing positive immunostaining for desmin (a and g) myotilin (b and h) and αB-cristallim (c and i) in both central cores (a-c) and dusty cores (g-i). Serial images of NADH and immunofluorescence for RyR1 and DHPR showing positive signal in central cores (e and f) and positive, but unmatching signal in dusty cores (m and n). (a-c: p26, 32 years; d-f: p40, 25 years; g-i: p13, 28 years; l-n: p7, 76 year)