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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration

Fig. 5

Formalin-fixed paraffin-embedded MTG sections stained for mouse anti-neurofilament light chain (clone DA2), one representative section from each Braak stage (I-VI) is displayed (a-f). The relationship between % NfL staining in the MTG and Braak staging at post-mortem (rho = − 0.34, p = 0.102) (g). A significant negative correlation between plasma NfL time point closest to death and % NfL staining in the MTG at post-mortem (rho = − 0.47, p < 0.01 (h)

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