Fig. 3

a Co-localization of transportin 3 and lamin A, and (b) of desmin and myotilin in the second muscle biopsy showing that, similarly to control muscle, transportin 3 is localized in the patient muscle mainly at the nuclei; and that desmin and myotilin are normally expressed. Bars = 50 μm. c COS7 cells transfected with wild-type or mutant TNPO3 cDNA showing correct localization to the nucleus of both mutant and wild-type transportin 3. Bar = 10 μm