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Table 7 The difference between number (± SE) of small-, medium-, and large-diameter axons in five CC segments in autistic and control subjects

From: Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects

Axon diameter

Group

S I

S II

S III

S IV

S V

< 0.651

C

8.789 (0.711)

6.955 (0.745)

1.924 (0.259)

0.862 (0.187)

4.427 (0.568)

A

4.701 (0.890)

5.422 (0.742)

1.153 (0.150)

0.817 (0.291)

5.881 (0.885)

p <

0.0025

0.164 (ns)

0.0253

0.8916 (ns)

0.1860 (ns)

Diff.

−46.5%

 

−40.1%

  

>  0.651 < 1.051

C

11.177 (0.930)

10.889 (0.530)

3.967 (0.639)

1.319 (0.144)

10.405 (0.934)

A

4.704 (0.972)

7.083 (0.836)

1.633 (0.332)

0.757 (0.178)

5.084 (0.974)

p <

0.0002

0.0014

0.0071

0.0294

0.0012

Diff.

−57.9%

−35.0%

−58.8%

−42.6%

−51.2%

> 1.051

C

5.933 (0.951)

7.099 (0.735)

3.985 (0.679)

1.529 (0.231)

10.389 (1.749)

A

1.527 (0.275)

2.993 (0.438)

0.825 (0.183)

0.465 (0.159)

2.334 (0.644)

p <

0.0015

0.0002

0.0014

0.0049

0.0015

Diff.

−74.2%

−57.8%

−79.3%

−69.6%

−77.6%

  1. SE standard error, CC corpus callosum, S segment, C control, A autism; Differ., difference. Standard errors in parentheses