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Table 7 The difference between number (± SE) of small-, medium-, and large-diameter axons in five CC segments in autistic and control subjects

From: Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects

Axon diameter Group S I S II S III S IV S V
< 0.651 C 8.789 (0.711) 6.955 (0.745) 1.924 (0.259) 0.862 (0.187) 4.427 (0.568)
A 4.701 (0.890) 5.422 (0.742) 1.153 (0.150) 0.817 (0.291) 5.881 (0.885)
p < 0.0025 0.164 (ns) 0.0253 0.8916 (ns) 0.1860 (ns)
Diff. −46.5%   −40.1%   
>  0.651 < 1.051 C 11.177 (0.930) 10.889 (0.530) 3.967 (0.639) 1.319 (0.144) 10.405 (0.934)
A 4.704 (0.972) 7.083 (0.836) 1.633 (0.332) 0.757 (0.178) 5.084 (0.974)
p < 0.0002 0.0014 0.0071 0.0294 0.0012
Diff. −57.9% −35.0% −58.8% −42.6% −51.2%
> 1.051 C 5.933 (0.951) 7.099 (0.735) 3.985 (0.679) 1.529 (0.231) 10.389 (1.749)
A 1.527 (0.275) 2.993 (0.438) 0.825 (0.183) 0.465 (0.159) 2.334 (0.644)
p < 0.0015 0.0002 0.0014 0.0049 0.0015
Diff. −74.2% −57.8% −79.3% −69.6% −77.6%
  1. SE standard error, CC corpus callosum, S segment, C control, A autism; Differ., difference. Standard errors in parentheses