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Table 4 Different patterns of distribution of the percentage (± SE) of small-, medium-, and large-diameter axons in segments I–V in autistic and control subjects

From: Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects

Axon diameter (μm) Group Percentage of axons in CC segments
S I S II S III S IV S V
<  0.651 C 34.6 (2.6) 28.0 (3.0) 20.5 (2.4) 24.3 (5.6) 19.1 (3.4)
A 43.1 (2.2) 35.0 (2.4) 38.9 (7.9) 37.8 (7.8) 46.6 (6.2)
p < 0.027* 0.093 0.058 0.175 0.0014**
Diff. + 24.42% ns ns ns + 143.7%
0.651–1.051 C 43.1 (1.3) 43.8 (1.3) 39.8 (1.2) 35.4 (2.8) 41.6 (2.0)
A 42.2 (1.8) 45.8 (2.1) 40.8 (5.3) 39.0 (4.2) 36.9 (3.4)
p < 0.696 0.429 0.858 0.472 0.261
Diff. ns ns ns ns ns
>  1.051 C 22.2 (1.9) 28.2 (2.1) 39.6 (3.3) 40.2 (3.8) 39.2 (3.2)
A 14.7 (1.3) 19.0 (2.1) 20.3 (3.0) 23.1 (3.8) 16.4 (3.1)
p < 0.005** 0.008** 0.007*** 0.010** 0.0001***
Diff. −34.02% −32.52% −48.82% −42.52 −58.2%
  1. SE Standard error, CC corpus callosum, S segment, C control, A autism; Diff., difference; ns, not significant. Standard errors in parentheses