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Table 3 Significance of difference of axon diameter, cross-sectional area, and myelin thickness between S I and other segments in the CC in autistic and control subjects (test for diversity of axons within segments)

From: Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects

Parameter

Group

S I/S II

S I/S III

S I/S IV

S I/S V

Axon diameter

C

0.055

0.0001***

0.003**

0.0004***

Axon cross-sectional area

C

0.049*

0.0004***

0.003**

0.0014***

Myelin sheath thickness

C

0.483

0.042*

0.101

0.200

Axon diameter

A

0.218

0.440

0.440

0.947

Axon cross-sectional area

A

0.174

0.174

0.174

0.931

Myelin sheath thickness

A

0.055

0.964

0.929

0.891

  1. P values incorporate multiple-comparison adjustments to maintain a false discovery rate (FDR) of 0.05. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001. S Segment, CC corpus callosum, C control, A autism