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Table 3 Significance of difference of axon diameter, cross-sectional area, and myelin thickness between S I and other segments in the CC in autistic and control subjects (test for diversity of axons within segments)

From: Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects

Parameter Group S I/S II S I/S III S I/S IV S I/S V
Axon diameter C 0.055 0.0001*** 0.003** 0.0004***
Axon cross-sectional area C 0.049* 0.0004*** 0.003** 0.0014***
Myelin sheath thickness C 0.483 0.042* 0.101 0.200
Axon diameter A 0.218 0.440 0.440 0.947
Axon cross-sectional area A 0.174 0.174 0.174 0.931
Myelin sheath thickness A 0.055 0.964 0.929 0.891
  1. P values incorporate multiple-comparison adjustments to maintain a false discovery rate (FDR) of 0.05. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001. S Segment, CC corpus callosum, C control, A autism
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Acta Neuropathologica Communications

ISSN: 2051-5960

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