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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Dichotomous scoring of TDP-43 proteinopathy from specific brain regions in 27 academic research centers: associations with Alzheimer’s disease and cerebrovascular disease pathologies

Fig. 4

Comparisons in percent of TDP-43 pathology in each brain region between hippocampal sclerosis present and absent. Note that there is a strong association between hippocampal sclerosis (HS) pathology and TDP-43 pathology. However, only a minority of cases, with or without comorbid HS pathology, have TDP-43 pathology detected in frontal cortex or spinal cord. a n = 4 had missing data on hippocampal sclerosis (HS) pathology. * p < 0.001. EC = entorhinal cortex; TCTX = temporal cortex

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