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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila

Fig. 6

Human TCERG1 influences TDP-43 production in HEK293T cells. a Western blot analysis of HEK293T cells with different combinations of GFP::TDP-43 and TCERG1 expression plasmids. Expression of both proteins were detected using anti-TDP-43 or anti-TCERG1 antibodies. Representative result from four independent experiments is presented. Proteins were sequentially extracted in RIPA (soluble) and Urea (insoluble) buffers. Total protein was used as the loading control. b, c The normalized expression of the TDP-43 protein is reported in the graphs (mean ± SEM). Protein levels were compared between both genotypes by using Student’s t-test. ***: p < 0.001, *: p < 0.05

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