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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: In vivo induction of membrane damage by β-amyloid peptide oligomers

Fig. 7

Treatment of hippocampal neurons with exogenous bacterial sphingomyelinase increases tau phosphorylation. a Cultured hippocampal neurons were treated with 2.5 mU/ml B. cereus sphingomyelinase, and tau immunoreactivity at the AT8 and PHF1 phospho-epitopes was quantified by immunofluorescence (normalized to total tau). b Cultured hippocampal neurons were treated with 2.5 mU B. cereus sphingomyelinase, and tau immunoreactivity at the AT8 and PHF1 phospho-epitopes was quantified by immunoblot (normalized to total tau). *p < 0.05, **p < 0.01 and ***p < 0.001 when compared with the vehicle control

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