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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: In vivo induction of membrane damage by β-amyloid peptide oligomers

Fig. 5

clp-4 deletion blocks endosome induction by CRY5B and sensitizes worms to CRY5B toxicity. a Induction of endosomes induced by CRY5B is blocked by the clp-4(ok2808) deletion mutation. *p < 0.05 when compared with the vehicle control. ###p < 0.001 when compared with the wt background. b Survival curves of C. elegans strains exposed to E. coli expressing CRY5B. Note that all three mutations that alter endosome accumulation also sensitize worms to CRY5B toxicity. *p < 0.05, **p < 0.01 compared to wild type control. NS = not significant

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