Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3

Table 1 Founder lines of MATR3^WT and MATR3^F115C mice used in the study

Transgene	Founder	Transmitting	Status	Use in paper	Reason for exclusion
MATR3^WT	8	Yes	Extinct	None	No/low expression
	9	Yes	Extinct	None	No/low expression
	59	Yes	Back-up line	Validation
	60	Yes	Extinct	None	No/low expression
	66	No	Extinct	None	Not transmitting
	1554	Yes	Extinct	Validation
	1563	Yes	Lead Line	Primary data
MATR3^F115C	70	Yes	Extinct	None	No/low expression
	72	Yes	Extinct	None	X-Linked
	1573	Yes	Extinct	Validation
	1576	Yes	Lead Line	Primary data
	1579	Yes	Extinct	Validation
MATR3^S85C	209	Yes	Extinct	None	No/low expression
	202	Yes	Extinct	None	No/low expression
	203	Yes	Extinct	None	No/low expression
	257	Yes	Extinct	None	No/low expression
	275	Yes	Extinct	None	No/low expression

ISSN: 2051-5960