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Table 1 Founder lines of MATR3WT and MATR3F115C mice used in the study

From: Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3

Transgene

Founder

Transmitting

Status

Use in paper

Reason for exclusion

MATR3WT

8

Yes

Extinct

None

No/low expression

9

Yes

Extinct

None

No/low expression

59

Yes

Back-up line

Validation

 

60

Yes

Extinct

None

No/low expression

66

No

Extinct

None

Not transmitting

1554

Yes

Extinct

Validation

 

1563

Yes

Lead Line

Primary data

 

MATR3F115C

70

Yes

Extinct

None

No/low expression

72

Yes

Extinct

None

X-Linked

1573

Yes

Extinct

Validation

 

1576

Yes

Lead Line

Primary data

 

1579

Yes

Extinct

Validation

 

MATR3S85C

209

Yes

Extinct

None

No/low expression

202

Yes

Extinct

None

No/low expression

203

Yes

Extinct

None

No/low expression

257

Yes

Extinct

None

No/low expression

275

Yes

Extinct

None

No/low expression

  1. Bold indicates lead lines