Fig. 3
From: SETD2 mutations in primary central nervous system tumors

Immunohistochemical staining for H3K36me3. a Examples of immunohistochemical staining for H3K36me3 in high grade gliomas with a truncating mutation in SETD2 (i) and wildtype control (ii); both images were taken at 200x magnification. b H scores for SETD2 mutant tumors and wildtype tumors. Averages for each group are shown as black squares and with error bars representing the standard deviation. c H scores calculated by two independent pathologists for SETD2 mutants plotted against allele frequency. Truncating mutations (TM), missense mutation (MM)