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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: SETD2 mutations in primary central nervous system tumors

Fig. 1

Demographics, locations and histologies of SETD2 mutant brain tumors. a Histograms of patient ages at time of tumor resection for the 19 cases presented in the current study (i) and from the TCGA database (ii). b Schematic representation of SETD2 mutant tumor locations within the CNS. c A schematic illustrating the proposed epigenetic effects of SETD2 alterations. d Representative histologies of SETD2 mutant tumors: Glioblastoma (i), Diffuse astrocytoma (ii), Pilocytic astrocytoma (iii), Atypical meningioma (iv), Medulloblastoma (v), Choroid plexus papilloma (vi). All tumors stained with Hematoxylin and Eosin. All photographs taken at 200x magnification. Truncating mutations (TM), missense mutation (MM)

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