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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: EphrinB/EphB forward signaling in Müller cells causes apoptosis of retinal ganglion cells by increasing tumor necrosis factor alpha production in rat experimental glaucomatous model

Fig. 4

Inhibition of ephrinB/EphB forward signaling reduces RGC apoptosis. a, Representative TUNEL staining images of RGC apoptosis in sham (control) (a), normal saline (NS)-injected (NS + G2w) (b), and PP2-injected (PP2 + G2w) (c) whole flat-mounted retinas on G2w in the regions at angle 0°. Scale bar, 50 μm, for all the images. b, Bar chart showing the average numbers of TUNEL-positive cells in whole flat-mounted retinas under different conditions. n = 4~ 5. **P < 0.01 vs. control; #P < 0.05 vs. NS + G2w group

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