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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations

Fig. 1

Illustrated location of Makurazaki city and the family trees of family A and B. a Geographical illustration of Japan. Makurazaki is a small city in the Kagoshima prefecture, located in the southernmost tip of Kyushu island. b Family trees of the two families harboring p.R1441H in LRRK2 mutation and living in Makurazaki city. Parkinson’s disease is shown as black and schizophrenia is shown as half black and half white. W/W = wildtype, W/M = heterozygous of c.4322G > A, M/M = homozygous of c.4322G > A. Diagonal line denotes deceased individuals. Asterisk represents autopsied cases

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