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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer’s disease

Fig. 6

Co-localization of MSI1 and MSI2 with tau in AD Brains (a) Representative epifluorescence image of AD cortex section stained with α-MSI1 and Pan-tau (Tau5) antibodies (white scale bar: 50 μm, magnification: 10X). (b) Representative epifluorescence image of AD cortex section stained with α-MSI2 and Pan-tau (Tau5) antibodies (white scale bar: 50 μm, magnification: 10X). (c) Inset 1: ten times zoomed image (green square in a) showed diffuse cytoplasmic co-localization of MSI1 and tau (white scale bar: 5 μm). Inset 2: ten times zoomed image (green square in c) showed cytoplasmic co-localization of MSI2 and tau (white scale bar: 5 μm). (d) PCC Graph represent colocalization coefficient between MSI1/Tau (PCC: 0.84 ± 0.07) and MSI2/Tau (PCC: 0.80 ± 0.06) in positive cells to both proteins showing high association in AD brain

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