Tumor location
|
Histone H3 mutational status
|
Total number of samples
|
---|
H3.3-G34R
|
H3.1-K27M
|
H3.3-K27M
|
H3.1 & H3.3-WT
|
---|
Cortex
|
6
|
0
|
0
|
35
|
41
|
Pons
|
0
|
13
|
26
|
6
|
45
|
Non-thalamic midline
|
0
|
0
|
2
|
12
|
14
|
Thalamic midline
|
0
|
0
|
12
|
7
|
19
|
- One hundred and nineteen high-grade glioma samples were divided in four groups according to their location either in the pontine (DIPG), cortical or thalamic area of the brain as well as the non-thalamic midline, i.e. spinal cord, cerebellum or peduncle tumors classified as ‘non-thalamic midlines’