Tumor location | Histone H3 mutational status | Total number of samples |
---|
H3.3-G34R | H3.1-K27M | H3.3-K27M | H3.1 & H3.3-WT |
---|
Cortex | 6 | 0 | 0 | 35 | 41 |
Pons | 0 | 13 | 26 | 6 | 45 |
Non-thalamic midline | 0 | 0 | 2 | 12 | 14 |
Thalamic midline | 0 | 0 | 12 | 7 | 19 |
- One hundred and nineteen high-grade glioma samples were divided in four groups according to their location either in the pontine (DIPG), cortical or thalamic area of the brain as well as the non-thalamic midline, i.e. spinal cord, cerebellum or peduncle tumors classified as ‘non-thalamic midlines’