Table 4 Values for spine morphology in CT100 and CT100(I716F) overexpression experiments

 Control (23)

0.29 [0.26–0.31]

0.62 [0.6–0.67]

0.09 [0.47–0.11]

 CT100 (6)

0.36 [0.27–0.4]

0.59 [0.54–0.64]

0.06 [0.04–0.09]

 GluN1^−/− (10)

0.29 [0.23–0.35]

0.6 [0.57–0.7]

0.07 [0.05–0.1]

 GluN1^−/− + CT100 (23)

0.27 [0.23–0.32]

0.64 [0.62–0.67]

0.07 [0.05–0.11]

 Kruskal Wallis test (Dunn’s posttest)

P = 0.1972 (Control vs CT100: p = 0.4813 Control vs GluN1−/: p > 0.9999; GluN1−/− vs GluN1−/− + CT100: p > 0.9999)

P = 0.1433 (Control vs CT100: p = 0.6288; Control vs GluN1^−/: p > 0.9999; GluN1^−/− vs GluN1^−/− + CT100: p = 0.5863)

P = 0.8439 (Control vs CT100: p > 0.9999; Control vs GluN1^−/: p > 0.9999; GluN1^−/− vs GluN1^−/− + CT100: p > 0.9999)

 Control (49)

0.32 [0.27–0.36]

0.61 [0.54–0.64]

0.08 [0.05–0.10]

 CT100(I716F) (19)

0.29 [0.27–0.33]

0.63 [0.59–0.66]

0.08 [0.06–0.08]

 GluN1^−/− (22)

0.32 [0.26–0.39]

0.56 [0.49–0.64]

0.1 [0.06–0.14]

 GluN1^−/− + CT100(I716F) (28)

0.32 [0.27–0.37]

0.61 [0.55–0.67]

0.07 [0.05–0.85]

 Kruskal Wallis test (Dunn’s posttest)

p = 0.529 (Control vs CT100(I716F): p = 0.53; Control vs GluN1^−/−: p > 0.9999; GluN1^−/− vs GluN1^−/− + CT100(I716F): p > 0.9999)

p = 0.198 (Control vs CT100(I716F): p = 0.5339; Control vs GluN1^−/−: p = 0.8345; GluN1^−/− vs GluN1^−/− + CT100(I716F): p = 0.3877)

p = 0.1098 (Control vs CT100(I716F): p > 0.9999; Control vs GluN1^−/−: p = 0.2132; GluN1^−/− vs GluN1^−/− + CT100(I716F): p = 0.0511)

 Control (11)

0.35 [0.32–0.37]

0.57 [0.53–0.62]

0.08 [0.03–0.11]

 CT100(I716F) (17)

0.36 [0.29–0.38]

0.57 [0.52–0.62]

0.07 [0.06–0.11]

 GluN2A^−/− (26)

0.38 [0.34–0.42]

0.54 [0.49–0.58]

0.1 [0.06–0.18]

 GluN2A^−/− + CT100(I716F) (21)

0.34 [0.3–0.38]

0.55 [0.52–0.61]

0.1 [0.08–0.13]

 Kruskal Wallis test (Dunn’s posttest)

p = 0.1208 (Control vs CT100(I716F): p > 0.999; Control vs GluN1^−/−: p = 0.9455; GluN1^−/− vs GluN1^−/− + CT100(I716F): p = 0.0586)

p = 0.2321 (Control vs CT100(I716F): p > 0.9999; Control vs GluN1^−/−: p = 0.2893; GluN1^−/− vs GluN1^−/− + CT100(I716F): p = 0.7813)

p > 0.1487 (Control vs CT100(I716F): p > 0.9999; Control vs GluN1^−/−: p > 0.9999; GluN1^−/− vs GluN1^−/− + CT100(I716F): p = 0.4372)

 Control (31)

0.36 [0.33–0.42]

0.55 [0.49–0.58]

0.08 [0.06–0.11]

 CT100(I716F) (45)

0.32 [0.28–0.4]

0.59 [0.53–0.6442]

0.07 [0.05–0.1]

 GluN2B^−/− (29)

0.33 [0.28–0.39]

0.56 [0.49–0.6]

0.11 [0.09–0.14]

 GluN2B^−/− + CT100(I716F) (16)

0.37 [0.33–0.44]

0.57 [0.5–0.6]

0.07 [0.04–0.09]

 Kruskal Wallis test (Dunn’s posttest)

P = 0.0105 (Control vs CT100(I716F): p = 0.0277; Control vs GluN2B^−/−: p = 0.043; GluN2B^−/− vs GluN2B^−/− + CT100(I716F): p = 0.1063)

P = 0.0319 (Control vs CT100(I716F): p = 0.0112; Control vs GluN2B^−/−: p = 0.6837; GluN2B^−/− vs GluN2B^−/− + CT100(I716F): p > 0.9999)

P = 0.0002 (Control vs CT100(I716F): p > 0.9999; Control vs GluN2B^−/−: p = 0.0066; GluN2B^−/− vs GluN2B^−/− + CT100(I716F): p = 0.0048)