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Table 10 mEPSC recordings from the 5xFAD mouse model

From: NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice

6 m DG
  WT (n = 24) 5xFAD (n = 23)  
Frequency [Hz] 0.73 [0.44–0.91] 0.66 [0.45–1.2] MW-test: p = 0.6612
Amplitude [pA] 10.08 [9.15–10.52] 10.64 [10.15–11.7] MW-test: p = 0.0013
1a DG
  WT (n = 27) 5xFAD (n = 21)  
Frequency [Hz] 0.80 [0.61–1.07] 0.61 [0.44–0.89] MW-test: p = 0.026
Amplitude [pA] 10.44 [8.54–11.95] 11.2 [8.94–11.86] MW-test: p = 0.47
  GluN1−/− (n = 17) 5xFAD/ GluN1−/− (n = 17)  
Frequency [Hz] 0.85 [0.68–1.26] 1.02 [0.55–1.56] MW-test: p = 0.8119
Amplitude [pA] 11.2 [10.24–12.84] 10.43 [9.66–12.31] MW-test: p = 0.394
  GluN2A−/− (n = 23) 5xFAD/ GluN2A−/− (n = 17)  
Frequency [Hz] 0.97 [0.61–1.13] 1.01 [0.64–1.98] MW-test: p = 0.2802
Amplitude [pA] 9.0 [8.38–9.93] 9.45 [8.97–10.72] MW-test: p = 0.1626
  GluN2B−/− (n = 21) 5xFAD/ GluN2B−/− (n = 16)  
Frequency [Hz] 1.26 [0.89–1.61] 1.31 [0.6–1.63] MW-test: p > 0.999
Amplitude [pA] 11.63 [10.72–12.14] 10.06 [9.88–12.92] MW-test: p = 0.3232