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Table 1 Neuropsychological performance of participants at the time of the [18F]flortaucipir scan

From: Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

 

GSS Participants

Early-Onset Alzheimer’s

Cognitive Normals

Patient A

Patient B

Patient #1

Patient #2

#1

#2

MoCA

22

18

18

17

29

26

CDR Global

0.5

1

0.5

0.5

0

0

CDR Sum of Boxes

1.5

7

3

3.5

0

0

Digit Span Forward

10

5

10

8

9

9

Digit Span Backward

8

5

10

6

12

10

Trail Making Test A

49

76

53

35

23

20

Trail Making Test B

129

300

209

159

61

38

WAIS Digit Symbol

36

20

40

27

68

82

Animal Fluency

15

8

13

21

24

23

Vegetable Fluency

9

11

11

3

18

13

Letter Fluency

25

11

36

26

36

25

MINT

31

28

27

30

32

24

RAVLT Immediate

41

22

27

22

56

51

RAVLT Delayed

7

3

0

0

11

8

Craft Stories Immediate

9

5

6

5

18

15

Craft Stories Delayed

10

4

2

0

17

16

Benson Figure Copy

16

10

14

17

15

15

Benson Figure Recall

10

8

2

0

12

13

GDS

4

4

2

2

1

0

FAS

7

13

14

17

1

0

NPI-Q

3

10

7

9

1

2

Finger Tapping – Dom

39

24

48

58

39

42

Finger Tapping – ND

33

25

36

52

43

40

  1. CDR Clinical Dementia Rating scale, Dom dominant hand, FAS Functional Assessment Scale, GDS Geriatric Depression Scale, GSS Gerstmann-Sträussler-Scheinker disease, MINT Multi-lingual Naming Test, MoCA Montreal Cognitive Assessment, ND non-dominant hand, NPI-QNeuropsychiatric Inventory Questionnaire, RAVLT Rey Auditory Verbal Learning Test, WAIS Wechsler Adult Intelligence Scale