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Table 1 Neuropsychological performance of participants at the time of the [18F]flortaucipir scan

From: Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

  GSS Participants Early-Onset Alzheimer’s Cognitive Normals
Patient A Patient B Patient #1 Patient #2 #1 #2
MoCA 22 18 18 17 29 26
CDR Global 0.5 1 0.5 0.5 0 0
CDR Sum of Boxes 1.5 7 3 3.5 0 0
Digit Span Forward 10 5 10 8 9 9
Digit Span Backward 8 5 10 6 12 10
Trail Making Test A 49 76 53 35 23 20
Trail Making Test B 129 300 209 159 61 38
WAIS Digit Symbol 36 20 40 27 68 82
Animal Fluency 15 8 13 21 24 23
Vegetable Fluency 9 11 11 3 18 13
Letter Fluency 25 11 36 26 36 25
MINT 31 28 27 30 32 24
RAVLT Immediate 41 22 27 22 56 51
RAVLT Delayed 7 3 0 0 11 8
Craft Stories Immediate 9 5 6 5 18 15
Craft Stories Delayed 10 4 2 0 17 16
Benson Figure Copy 16 10 14 17 15 15
Benson Figure Recall 10 8 2 0 12 13
GDS 4 4 2 2 1 0
FAS 7 13 14 17 1 0
NPI-Q 3 10 7 9 1 2
Finger Tapping – Dom 39 24 48 58 39 42
Finger Tapping – ND 33 25 36 52 43 40
  1. CDR Clinical Dementia Rating scale, Dom dominant hand, FAS Functional Assessment Scale, GDS Geriatric Depression Scale, GSS Gerstmann-Sträussler-Scheinker disease, MINT Multi-lingual Naming Test, MoCA Montreal Cognitive Assessment, ND non-dominant hand, NPI-QNeuropsychiatric Inventory Questionnaire, RAVLT Rey Auditory Verbal Learning Test, WAIS Wechsler Adult Intelligence Scale