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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients

Fig. 1

Selected electron micrographs of human brain biopsies from iNPH patients. a Interaction of mitochondria with plasma membrane (PM), nucleus (n), Golgi and lisosomes (L) (from left to right). b Interactions between ER and mitochondria (m). Small stretches of ER in contact with mitochondria (top left and right), longer contacts of ER in contact with mitochondria (bottom panel, left and middle), and a point contact (bottom, right). c MERCS in pre-synaptic (left) and post-synaptic (right) density. Black arrow head – mitochondria-PM interaction, black arrow – mitochondria-nucleus interaction, # – mitochondria-lysosome interaction, white arrow – ER, white arrow head – MERCS, * - synapse. Scale bar = 500 nm

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