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Table 1 Serial transmission of rPrPresPE + PolyA in Golden Syrian hamsters

From: Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein

Passage nsick/nt a n PrPSc/nt b inc time c, dpi duration d, days
1st 3/4 4/4 517 105
2nd e 6/6 6/6 274, 4 at 300, 324 110, 122, 126, 133, 134, 160
2nd e 5/5 5/5 274, 2 at 288, 324, 335 105, 116, 119, 146, 166
  1. a The number of animals that developed clinical signs per total number of animals
  2. b The number of animals with PrPSc on Western blot per total number of animals
  3. c Incubation time to first clinical signs
  4. d Duration of clinical disease from the first clinical signs to the terminal stage
  5. e For the second passage, two inocula were prepared using two individual animals from the first passage