Anaplastic astrocytoma IDH-wildtype N (% of Total) |
Glioblastoma IDH-wildtype N (% of Total) |
Anaplastic astrocytoma IDH-mutant N (% of Total) |
Glioblastoma IDH-mutant N (% of Total) |
Anaplastic oligodendroglioma IDH-mutant and 1p/19q-codeleted N (% of Total) | |
---|---|---|---|---|---|
Total | 6 | 138 | 80 | 124 | 227 |
Median age, years (range) | 52 (26–60) | 59 (16–83) | 37 (18–75) | 38 (19–78) | 48 (19–80) |
Gender | |||||
Female | 2 (33) | 60 (44) | 35 (44) | 53 (43) | 101 (44) |
Male | 4 (67) | 78 (56) | 45 (56) | 71 (57) | 126 (56) |
Median preoperative KPS% (range) | 90 (90–100) | 80 (40–100) | 90 (60–100) | 90 (50–100) | 90 (50–100) |
Resection | |||||
Gross total resection | 1 (17) | 57 (41) | 18 (23) | 34 (27) | 81 (36) |
Subtotal resection | 2 (33) | 37 (27) | 38 (48) | 43 (35) | 58 (26) |
Biopsy | 2 (33) | 25 (18) | 9 (11) | 35 (28) | 66 (29) |
Unknown | 1 (17) | 19 (14) | 15 (19) | 12 (10) | 22 (10) |
Adjuvant treatment | |||||
None | 0 | 3 (2) | 3 (4) | 1 (1) | 9 (4) |
RT alone | 1 (17) | 3 (2) | 5 (6) | 3 (2) | 42 (19) |
RT + PCV | 0 | 2 (1) | 15 (19) | 16 (13) | 72 (32) |
PCV alone | 0 | 2 (1) | 0 | 0 | 6 (3) |
RT + TMZ | 5 (83) | 104 (75) | 38 (48) | 73 (59) | 70 (31) |
TMZ alone | 0 | 5 (4) | 3 (4) | 4 (3) | 5 (2) |
No data | 0 | 19 (14) | 16 (20) | 27 | 23 (10) |
IRS Score | |||||
IRS = 0 | 5 (83) | 86 (62) | 31 (39) | 47 (38) | 69 (30) |
1 ≥ IRS < 4 | 0 | 33 (24) | 27 (34) | 46 (37) | 51 (22) |
IRS ≥ 4 | 1 (17) | 19 (14) | 22 (27) | 31 (25) | 107 (47) |