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Table 1 Characteristics of the patient population (N = 583)

From: Somatostatin receptor 2A protein expression characterizes anaplastic oligodendrogliomas with favorable outcome

  Anaplastic astrocytoma
IDH-wildtype
N (% of Total)
Glioblastoma
IDH-wildtype
N (% of Total)
Anaplastic astrocytoma
IDH-mutant
N (% of Total)
Glioblastoma
IDH-mutant
N (% of Total)
Anaplastic oligodendroglioma
IDH-mutant and 1p/19q-codeleted N (% of Total)
Total 6 138 80 124 227
Median age, years (range) 52 (26–60) 59 (16–83) 37 (18–75) 38 (19–78) 48 (19–80)
Gender
 Female 2 (33) 60 (44) 35 (44) 53 (43) 101 (44)
 Male 4 (67) 78 (56) 45 (56) 71 (57) 126 (56)
Median preoperative KPS% (range) 90 (90–100) 80 (40–100) 90 (60–100) 90 (50–100) 90 (50–100)
Resection
 Gross total resection 1 (17) 57 (41) 18 (23) 34 (27) 81 (36)
 Subtotal resection 2 (33) 37 (27) 38 (48) 43 (35) 58 (26)
 Biopsy 2 (33) 25 (18) 9 (11) 35 (28) 66 (29)
 Unknown 1 (17) 19 (14) 15 (19) 12 (10) 22 (10)
Adjuvant treatment
 None 0 3 (2) 3 (4) 1 (1) 9 (4)
 RT alone 1 (17) 3 (2) 5 (6) 3 (2) 42 (19)
 RT + PCV 0 2 (1) 15 (19) 16 (13) 72 (32)
 PCV alone 0 2 (1) 0 0 6 (3)
 RT + TMZ 5 (83) 104 (75) 38 (48) 73 (59) 70 (31)
 TMZ alone 0 5 (4) 3 (4) 4 (3) 5 (2)
 No data 0 19 (14) 16 (20) 27 23 (10)
IRS Score
 IRS = 0 5 (83) 86 (62) 31 (39) 47 (38) 69 (30)
 1 ≥ IRS < 4 0 33 (24) 27 (34) 46 (37) 51 (22)
 IRS ≥ 4 1 (17) 19 (14) 22 (27) 31 (25) 107 (47)
  1. Abbreviations: IRS Immunoreactive score; KPS Karnofsky Performance Status Scale; PCV Procarbazine + Lomustine + Vincristine; RT Radiotherapy; TMZ Temozolomide