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Table 3 Quantification of the neuropathological changes. Synaptic proteins synaptophysin (SYP) and PSD-95 in Alzheimer’s disease cases revealed by ELISA (μg/ml)

From: Systemic infection modifies the neuroinflammatory response in late stage Alzheimer’s disease

Protein concentration (μg/ml)

AD-

AD+

P value

SYP

1.06 (0.71, 1.74)

1.39 (0.74, 2.46)

0.242

PSD-95

1.95 (0.10, 3.35)

1.92 (1.04, 2.48)

0.374

SYP/PSD-95

0.54 (0.34, 1.15)

0.76 (0.40, 1.50)

0.269

  1. Values are median ± IQR; p value by Mann-Whitney test
  2. SYP Synaptophysin, AD Alzheimer’s disease cases, − died without systemic infection, + died with systemic infection, IQR interquartile range