Fig. 5

Area under the ROC curve. The levels of 10 metabolites are significantly different between IDH-mutant and IDH-WT gliomas. The area under the ROC curve for these metabolites individually and combined is shown. The area under the ROC curve for these 10 metabolites ranged from 0.724 to 0.888. In combination, the area under the ROC curve for the 10 metabolites was 0.918. The levels of these metabolites in CSF can help discriminate patients with IDH-mutant gliomas from IDH-WT gliomas