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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response

Fig. 1

a CSF ddPCR results from experimental samples correlated with contrast-enhancing and total tumor cross-sectional area on MRI. b ddPCR of multi-focal sampling shows K27M copy number varies between tumor (purple) and CSF (orange) regions c Co-culture scheme of bioluminescent human DIPG007 cells with NHAs. d DIPG007 cells release ctDNA in proportion to their proliferation. e 8 Gy radiation results in an increase in mutant ctDNA from DIPG007 cells

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Acta Neuropathologica Communications

ISSN: 2051-5960

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